Research of the centre focuses on both basic and translational biomedical sciences. Using cutting-edge single-cell sequencing, CRISPR/CAS9 genome editing, super-resolution imaging and mouse gene targeting technologies , we are tackling fundamental questions on stem cell biology (skeleton, muscle, and blood stem/progenitor cell fate determination, somatic reprogramming, pluripotency regulation and direct lineage conversion), developmental biology (skeleton and placenta development), platelet and thrombosis regulation, scavenger receptor in lipid metabolism, and senescence/aging. In particular, the center, led by Prof Hongwei Ouyang, is recognized as one of the leaders in the area of skeleton system regeneration by employing interdisciplinary approaches which integrate biomedical science, material science, chemistry science and engineering technologies. Principle Investigators (PIs) of the centre are able to compete for national key grants and laboratories are currently well-funded by key grants from both Natural Science Foundation of China (NSFC) and Ministry of Science and Technology of China (MOST).

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