Two distinct regulatory pathways govern Cct2-Atg8 binding in the process of solid aggrephagy 2024-10-09
Gasdermin D-mediated metabolic crosstalk promotes tissue repair 2024-10-09
Structural basis of adenine nucleotides regulation and neurodegenerative pathology in ClC-3 exchanger 2024-10-09
“SWI/SNF chromatin-remodeling factor BAF60b restrains inflammatory diseases by affecting regulatory T cells migration 2024-10-09
Structural Basis of Tethered Agonism and G protein coupling of Protease-Activated Receptor 2024-10-09
An inhibitory mechanism of AasS, an exogenous fatty acid scavenger: Implications for re-sensitization of FAS II antimicrobials 2024-10-09
Identification of BAF60b as a chromatin remodeling checkpoint of diet-induced fatty liver disease 2024-10-09
Base-resolution m5C profiling across the mammalian transcriptome by bisulfite-free enzyme-assisted chemical labeling approach 2024-08-29
Phase separation-competent FBL promotes early pre-rRNA processing and translation in acute myeloid leukaemia 2024-08-29
Hematopoietic stem and progenitor cell membrane-coated vesicles for bone marrow targeted leukaemia drug delivery 2024-08-29
GRP75-dependent mitochondria-ER contacts ensure cell survival during early mouse thymocyte development 2024-08-07
Ca2+-triggered Atg11-Bmh1/2-Snf1 complex assembly initiates autophagy upon glucose starvation 2024-08-07
Structural basis of promoter recognition by Staphylococcus aureus RNA polymerase 2024-06-12
Hsc70 promotes anti-tumor immunity by targeting PD-L1 for lysosomal degradation 2024-06-07
TFPI from erythroblasts drives heme production in central macrophages promoting erythropoiesis in polycythemia 2024-06-07
Discovery of a Bacterial Hydrazine Transferase That Constructs the N-Aminolactam Pharmacophore in Albofungin Biosynthesis 2024-06-07
UFL1 triggers replication fork degradation by MRE11 in BRCA1/2-deficient cells 2024-06-07
Molecular Determinant Underlying Selective Coupling of Primary G-protein by Class A GPCRs 2024-06-07
Neutrophil Extracellular Traps-Inhibiting and Fouling-Resistant Polysulfoxides Potently Prevent Postoperative Adhesion, Tumor Recurrence and Metastasis 2024-06-07
Neutralization of EG.5, EG.5.1, BA.2.86, and JN.1 by antisera from dimeric receptor-binding domain subunit vaccines and 41 human monoclonal antibodies 2024-06-06