BAF60a-dependent chromatin remodeling preserves β-cell function and contributes to the therapeutic benefits of GLP-1R agonists 2025-10-20
Elastin-derived extracellular matrix fragments drive aging through innate immune activation 2025-10-13
Macrophage ferroptosis potentiates GCN2 deficiency induced pulmonary venous arterialization 2025-09-28
A CD4 + T lymphocyte–specific TCR/GSDMD/IL-2 axis facilitates antitumor immunity 2025-09-28
E3 ligase RAD18 targets phosphorylated IRF3 to terminate IFNB1 transcription 2025-09-11
Physical and chemical niche of human growth plate for polarized bone development 2025-09-11
Metabolic regulation of key developmental events during mammalian embryogenesis 2025-09-08
Bispecific killer cell engager-secreting CAR-T cells redirect natural killer specificity to enhance antitumour responses 2025-09-08
Gasdermin-D-mediated epithelial-immune circuit synchronizes nutrient absorption and host defense in the small intestine 2025-09-08
Discovery and Structural Basis of Endogenous and Exogenous Inhibitors of the Proton-activated-chloride Channel 2025-09-08
Modeling the vertebrate regulatory sequence landscape by UUATAC-seq and deep learning 2025-09-08
Targeting of hyperlipid-producing senescent synovial fibroblasts to ameliorate cartilage degeneration 2025-06-24
Medial preoptic CCKAR mediates anxiety and aggression induced by chronic emotional stress in male mice 2025-05-26
Activin A-activated ALK4 induces pathogenic Th17 involved endothelial-mesenchymal transition in systemic lupus erythematosus-associated pulmonary arterial hypertension 2025-05-25
Baf60c in skeletal muscle regulates adipose tissue thermogenesis via Musclin-mediated endocrine signaling 2025-05-09
SLC7A11 is an unconventional H+ transporter in lysosomes 2025-04-27
Selective identification of epigenetic regulators at methylated genomic sites by SelectID 2025-04-27
ZBP1 senses splicing aberration through Z-RNA to promote cell death 2025-04-27
A. faecalis induces intestinal T helper 17 cells by promoting E3 ubiquitin ligase Trim21-mediated E3 ubiquitin ligase Fbxw7 degradation 2025-04-11
Proton perception and activation of a proton-sensing GPCR 2025-04-11